Hypertension or the High blood pressure is the biggest risk factor for the heart disease. This is also the leading cause of a death in the country United States. But the new study has also found about the two classes of the medication. That commonly used for lowering the blood pressure. It could be present the risk of death all their own. Death risk increased with two blood pressure drugs while lowering the blood pressure.
The scientists found in research that the individuals with the high blood pressure. And who also used the alpha-blocker & alpha-2 agonist for controlling the blood pressure. That showed the increase in the blood pressure changes that could increase the risk of mortality. The blood pressure also forced the blood to pushes opposite to the wall of an artery.
If the systolic blood of a person is 130mm or higher than this, it will be considered as high blood pressure. When the thing comes to the treatment of hypertension then the goal is the lowering of the blood pressure. For this, the lifestyles must be changed. The healthy diet, medication and the physical activity is important aspects.
How Did Death risk increase with two blood pressure drugs?
The study also revealed that two classes of the blood pressure medications linked to hypertension. That change in subjects the alpha blockers & the alpha-2 agonist’s. The Research found that the use of these 2 medications is not good for the treatment of high blood pressure.
The Alpha blockers include the mesylate, doxazosin, and the prazosin hydrochloride. It works by the dilating of the blood vessel. The Alpha-2 agonists include the methyldopa. That works by the targeting the activity of the sympathetic nervous system. It reduces the constriction of a blood vessel.
Alpha blockers used for the treatment of the blood pressure but it also have some side effects. Research also found that the use of this drugs leads to heart failure.
- Weight gain
- A headache
- Pounding of heartbeat
The Alpha blocker may also increase and decrease the effect of the other medication that patient takes. So, before the take of the alpha-blocker. Always be sure that doctor should know about the other medication you are taking. Other medications are calcium channel blocker, the beta blocker. And the calcium channel blocker or the medications for the erectile dysfunction.
The Alpha-2 agonists bind to the α-receptors on the smooth muscle of vascular. It also induces the smooth contraction & also the vasoconstriction. The mimicking effects of the nerve activation of the sympathetic adrenergic to the blood vessel.
The Alpha-agonists also constrict both veins and arteries. The vasoconstrictor effects more pronounced in the vessels of arterial resistance. The constriction of a resistance vessel the small arteries. And the arterioles increases the resistance of the systemic vascular. Whereas the constriction of venous capacitance vessel also increases the venous pressure.
So, Death risk increased with two blood pressure drugs are these. Save yourself from the wrong medication and always be aware of your disease information.